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Are there infinitely many $n$ such that if \[n(n+1) = \prod_i p_i^{k_i}\] is the factorisation into distinct primes then all exponents $k_i$ are distinct?
It is likely that there are infinitely many primes $p$ such that $8p^2-1$ is also prime, in which case this is true with exponents $\{1,2,3\}$, letting $n=8p^2$.
Additional thanks to: Euro Vidal Sampaio