In [Er69b] Erdős asks for even a construction whose largest clique or independent set has size $o(n^{1/2})$, which is now known.
Cohen [Co15] (see the introduction for further history) constructed a graph on $n$ vertices which does not contain any clique or independent set of size \[\geq 2^{(\log\log n)^{C}}\] for some constant $C>0$. Li [Li23b] has recently improved this to \[\geq (\log n)^{C}\] for some constant $C>0$.
This problem is #4 in Ramsey Theory in the graphs problem collection.