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Is there a permutation $a_1,a_2,\ldots$ of the positive integers such that $a_k+a_{k+1}$ is always prime?
Asked by Segal. The answer is yes, as shown by Odlyzko.

Watts has suggested that perhaps the obvious greedy algorithm defines such a permutation - that is, let $a_1=1$ and let \[a_{n+1}=\min \{ x : a_n+x\textrm{ is prime and }x\neq a_i\textrm{ for }i\leq n\}.\] In other words, do all positive integers occur as some such $a_n$? Do all primes occur as a sum?