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Suppose $a_1<a_2<\cdots$ is a sequence of integers such that for all integer sequences $t_n$ with $t_n\geq 1$ the sum \[\sum_{n=1}^\infty \frac{1}{t_na_n}\] is irrational. How slowly can $a_n$ grow?
One possible definition of an 'irrationality sequence' (see also [263] and [264]). An example of such a sequence is $a_n=2^{2^n}$, while a non-example is $a_n=n!$. It is known that if $a_n$ is such a sequence then $a_n^{1/n}\to\infty$.