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Does there exist $S\subseteq \mathbb{R}^2$ such that every set congruent to $S$ (that is, $S$ after some translation and rotation) contains exactly one point from $\mathbb{Z}^2$?
An old question of Steinhaus. Erdős was 'almost certain that such a set does not exist'.

In fact, such a set does exist, as proved by Jackson and Mauldin [JaMa02]. Their construction depends on the axiom of choice.

Additional thanks to: Vjekoslav Kovac