Odlyzko has checked this up to $10^7$. Granville and Soundararajan [GrSo98] have proved that this is very related to the problem of finding primes $p$ for which $2^p\equiv 2\pmod{p^2}$ (for example this conjecture implies there are infinitely many such $p$).

This is equivalent to asking whether every $n$ not divisible by $4$ is the sum of a squarefree number and a power of two. Erdős thought that proving this with two powers of 2 is perhaps easy, and could prove that it is true (with a single power of two) for almost all $n$.