Erdős called this 'perhaps my first serious problem' (in [Er98] he dates it to 1931). The powers of $2$ show that $2^n$ would be best possible here. The trivial lower bound is $N \gg 2^{n}/n$, since all $2^n$ distinct subset sums must lie in $[0,Nn)$. Erdős and Moser [Er56] proved \[ N\geq (\tfrac{1}{4}-o(1))\frac{2^n}{\sqrt{n}}.\] (In [Er85c] Erdős offered \$100 for any improvement of the constant $1/4$ here.)

A number of improvements of the constant have been given (see [St23] for a history), with the current record $\sqrt{2/\pi}$ first proved in unpublished work of Elkies and Gleason. Two proofs achieving this constant are provided by Dubroff, Fox, and Xu [DFX21], who in fact prove the exact bound $N\geq \binom{n}{\lfloor n/2\rfloor}$.

In [Er73] and [ErGr80] the generalisation where $A\subseteq (0,N]$ is a set of real numbers such that the subset sums all differ by at least $1$ is proposed, with the same conjectured bound. (The second proof of [DFX21] applies also to this generalisation.)

This problem appears in Erdős' book with Spencer [ErSp74] in the final chapter titled 'The kitchen sink'. As Ruzsa writes in [Ru99] "it is a rich kitchen where such things go to the sink".

The sequence of minimal $N$ for a given $n$ is A276661 in the OEIS.

See also [350].